| abstract |
The present disclosure provides antibodies that specifically bind the human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind human OX40 and modulate OX40 activity, eg, enhance, activate, or induce OX40 activity, or decrease, inactivate, or inhibit OX40 activity. The present disclosure also provides methods of treating disorders, such as cancer, by administering an antibody that specifically binds human OX40 and modulates OX40 activity, eg, enhances, activates, or induces OX40 activity. Also provided are methods of treating autoimmune or inflammatory diseases or disorders by administering antibodies that specifically bind human OX40 and modulate OX40 activity, eg, reduce, inactivate, or inhibit OX40 activity. |