http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108129490-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18 |
| filingDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108129490-B |
| titleOfInvention | Method for preparing everolimus amorphous solid |
| abstract | The invention discloses a method for preparing everolimus amorphous solid, and belongs to the field of medicines. The method comprises the following steps: (1) dissolving everolimus in an organic solvent to obtain an everolimus-containing solution; wherein the organic solvent is nitrile, alcohol, ketone or furan; (2) and (2) adding water into the solution obtained in the step (1), concentrating, filtering and drying to obtain everolimus amorphous solid. The method has the advantages of convenient operation, large amount of processed samples, convenient industrialization, high yield up to 94 percent; meanwhile, as the mother liquor almost only leaves water at last, the solubility of everolimus is almost avoided, the mother liquor is not required to be recycled and refined, the loss in the mother liquor is almost negligible, the processes are omitted, and the post-treatment cost is reduced. |
| priorityDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.