| abstract |
The embodiment of the present invention provides azide trifluoromethoxy compound and its synthesis method, wherein the structure of azide trifluoromethoxy compound is shown in the following formula (1) or formula (2): the azide trifluoromethoxy compound provided by the present invention Fluoromethoxy compounds, which have both azido and trifluoromethoxy groups, can be further transformed into trifluoromethoxy compounds with various nitrogen-containing functional groups, which can be used as intermediates in medicine, pesticides, and materials. In addition, the present invention provides a new method for the simple and convenient synthesis of azidotrifluoromethoxy compounds through mild photocatalytic reaction conditions, and the substrate has a wide range of applications, no matter whether the substrate contains electron-withdrawing or electron-donating Electronic vinyl substrates can get better yields, and this method can be well applied to the last step of azidotrifluoromethoxy functionalization of complex natural product molecules, and has a wide range of applications. |