http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108126245-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-32 |
filingDate | 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108126245-B |
titleOfInvention | An orthopedic titanium alloy implant material and preparation method thereof |
abstract | The invention discloses an orthopedic titanium alloy implant material and a preparation method thereof, and relates to the technical field of medical materials. The implant material uses a medical titanium alloy subjected to solid solution treatment as a substrate, and the temperature of the solid solution treatment of the substrate is 935-983° C. The surface of the substrate is modified with chitosan, the chitosan is grafted with β-cyclodextrin, the β-cyclodextrin is loaded with a hydrophobic drug, the surface of the substrate is formed with a hydroxyapatite coating, and the hydroxyapatite The coating is a microporous coating formed by micro-arc oxidation technology. The invention can make the hardness of the titanium alloy closer to the hardness of the bone, avoid the damage to the bone after the titanium alloy is implanted into the human body, and is beneficial to improve the biological fixation after the titanium alloy is implanted into the human body, and the ingrowth of the bone tissue. At the same time, the drug components are slowly released in the process of bone wound healing, so that the drug in the receiving system can maintain an effective concentration for a long time, which can lastingly promote osteogenesis and angiogenesis, accelerate bone wound healing, and prevent wound inflammation and other conditions. |
priorityDate | 2018-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.