http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108125926-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5176 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 |
| filingDate | 2017-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108125926-B |
| titleOfInvention | Preparation method and application of magnetic nanoparticles spanning blood-eye barrier |
| abstract | The invention discloses a preparation method and application of magnetic nanoparticles spanning blood-eye barriers, which comprises the following steps: taking purified bacterial magnetosomes BMs, and combining amino terminals of the bacterial magnetosomes BMs with sulfydryl of cysteine in TAT polypeptide by using N-succinimide 3- (2-pyridine dithio) propionate as a cross-linking agent to obtain magnetic nanoparticles capable of crossing blood eye barriers, wherein the magnetic nanoparticles are TAT-BMs composite carriers. The magnetic nano-particles can cross the blood-eye barrier, and the application potential of the magnetic nano-material in the treatment of eye diseases is expanded. |
| priorityDate | 2017-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.