http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108118035-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-13022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0073 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 |
filingDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108118035-B |
titleOfInvention | Cyclohexanone monooxygenase and application thereof |
abstract | The invention discloses cyclohexanone monooxygenase and application thereof, in particular discloses cyclohexanone monooxygenase obtained by site-directed mutagenesis and application thereof, and compared with SEQ ID NO:1, the amino acid sequence of the cyclohexanone monooxygenase has gene mutation at least one of the following sites: ser at position 386 to become asparagine Asn, and Ser at position 435 to become threonine Thr. Experiments show that the cyclohexanone monooxygenase disclosed by the invention can be used for catalytically converting an omeprazole thioether substrate with high concentration into esomeprazole. |
priorityDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 377.