http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108101906-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 |
filingDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108101906-B |
titleOfInvention | Preparation method of cyclopentyl [ f ] pyrrolo [2,1,5-cd ] indolizine derivative |
abstract | A preparation method of cyclopentyl [ f ] pyrrolo [2,1,5-cd ] indolizine derivatives belongs to the technical field of organic synthetic chemistry, and can solve the problem that the cyclopentyl [ f ] pyrrolo [2,1,5-cd ] indolizine derivatives are difficult to prepare due to the complex molecular structure and spatial configuration of the pyrrolo [2,1,5-cd ] indolizine derivatives. The method uses pyrrolo [2,1,5-cd ] indolizine derivatives containing iodine atoms and chlorine atoms as raw materials, converts the derivatives into ether derivatives, and further obtains the cyclopentyl [ f ] pyrrolo [2,1,5-cd ] indolizine derivatives under the catalytic action of ruthenium trichloride and silver trifluoromethanesulfonate. The invention efficiently and stereoselectively synthesizes the cyclopentyl [ f ] pyrrolo [2,1,5-cd ] indolizine derivative through two-step reaction, the reaction yield is high, and no by-product is generated. |
priorityDate | 2017-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.