http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108101870-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-24 |
| filingDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108101870-B |
| titleOfInvention | Preparation method of active ingredient for selectively treating glaucoma and related salt thereof |
| abstract | The invention discloses a preparation method of an active component for selectively treating glaucoma and a related salt thereof, belonging to the field of pharmaceutical chemicals. The invention uses 4-substituted oxy-5-substituted oxy-2-methylbenzoic acid, (2S) - (+) -glycidyl ester group substituted sulfonate, 2-methyl-2-nitropropylamine, tetrahydrofuran-3-formic acid, N- (2-methyl-2-nitropropyl) tetrahydrofuran-3-formamide, N- (2-methyl-2-aminopropyl) tetrahydrofuran-3-formamide, (S) -4, 5-disubstituted-2-methylbenzoic acid epoxy ethyl methyl ester, 4, 5-disubstituted-2-methylbenzoic acid ((2S) -2-hydroxy-3- ((2-methyl-1- (tetrahydrofuran-3-formamido) propyl-2-yl) methyl benzoate ) At least one compound in the ester and the related salt thereof is used as a starting material or an intermediate for preparation, the yield of 77 percent can be obtained, the reaction selectivity is good, and the product purity is high. |
| priorityDate | 2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.