| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-4382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D04H1-4309
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/D01D5-0061 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D01D5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4309
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate |
2018-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108096225-B |
| titleOfInvention |
Nanofiber membrane containing calcitonin liposome and preparation method and application thereof |
| abstract |
The invention belongs to the field of drug sustained-release materials, and discloses a nanofiber membrane containing calcitonin liposome and a preparation method and application thereof. Carrying out rotary evaporation on soybean lecithin, cholesterol and an organic solvent to obtain a lipoid film, then adding a calcitonin phosphate buffer solution to prepare a calcitonin-loaded nano liposome, and adding the calcitonin-loaded nano liposome into a pectin solution to obtain a calcitonin-loaded pectin-coated liposome; and adding the obtained calcitonin-carrying pectin coated liposome into a mixed solution of polyvinyl alcohol and sodium alginate, and preparing a membrane through electrostatic spinning to obtain the nano-fiber membrane containing the calcitonin liposome. The invention can improve the bioavailability and stability of the calcitonin by adding the calcitonin liposome and the pectin coating. |
| priorityDate |
2018-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |