http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108084163-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108084163-B |
titleOfInvention | A method of preparing small particle voriconazole |
abstract | The present invention provides a kind of new methods for preparing small particle voriconazole, it is characterized by: voriconazole chirality salt is dissolved in hydrophilic organic solvent or aqueous organic solvent, above-mentioned solution is added in alkaline aqueous solution, solid is precipitated, is separated by filtration to obtain voriconazole.Voriconazole crystal form prepared by the present invention is B crystal form, and product is easy to crush, and products obtained therefrom size distribution D90 is less than 40 μm.Preparation method provided by the present invention is easy to operate, is very beneficial for industrialized production. |
priorityDate | 2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.