http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108079302-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H70-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-382 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108079302-B |
| titleOfInvention | Application of Nrf2 agonist in preparation of medicine for treating psoriasis |
| abstract | The invention discloses application of an Nrf2 agonist in preparation of a medicine for treating psoriasis and a personalized medication method of an Nrf2 agonist. The invention analyzes the clinical symptoms and pathological tissue pathological sections of the mice after medication treatment by establishing a mouse animal model infected with psoriasis, and simultaneously takes healthy mice, mice which are not treated by medication after the psoriasis is infected and mice which are treated by the approved medicament for treating the psoriasis after the psoriasis is infected as references, and experimental results show that in the aspects of clinical symptoms, skin tissue lesion and the like, the Nrf2 agonists astemizole and bithiol have certain treatment effect on the psoriasis, thereby providing a new choice for clinical medication. The invention also provides a personalized medicine taking method based on the gene expression data of the patient, which can effectively predict the medicine effect of the Nrf2 agonist on the specific psoriasis patient and guide personalized medicine taking. |
| priorityDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.