| abstract |
The invention relates to an epsilon-polylysine bionic antibacterial film and a preparation method thereof, which are characterized in that a gelatinizing aqueous solution containing epsilon-polylysine, chitosan, hyaluronic acid, gelatin, polyvinyl alcohol and glycerol is prepared, then a cross-linking agent is added to carry out cross-linking reaction in a patterned template to obtain gel, and the epsilon-polylysine bionic antibacterial film is obtained after neutralization, cleaning and drying. The epsilon-polylysine bionic antibacterial membrane has good antibacterial and moisturizing properties, and in addition, the composition of the epsilon-polylysine bionic antibacterial membrane is similar to that of an extracellular matrix and has a patterned surface, so that the epsilon-polylysine bionic antibacterial membrane can promote the adhesion, growth and migration of epithelial cells. Therefore, the epsilon-polylysine bionic antibacterial film can be used as a skin wound dressing, and the wound repair effect is improved. |