| abstract |
The present invention relates to virus-like particles of the plant virus Cucumber Mosaic Virus (CMV), and in particular to modified VLPs of CMV comprising Th cell epitopes, in particular generic Th cell epitopes. Furthermore, these modified VLPs preferably serve as vaccine platforms for generating immune responses, in particular antibody responses, against antigens linked to the modified VLPs. The presence of Th cell epitopes, in particular generic Th cell epitopes, leads to a further increase in the immune response generated. |