| abstract |
The present disclosure provides antibodies and compositions comprising such antibodies that specifically bind to the human glucocorticoid-induced TNFR family-related receptor (GITR). In a specific aspect, antibodies specifically bind to human GITR and modulate GITR activity, eg, GITR activity is enhanced, activated or induced using such antibodies. The present disclosure also provides methods of treating disorders, such as cancer and infectious diseases, by administering antibodies that specifically bind to human GITR and modulate GITR activity, eg, enhance, activate or induce GITR activity. |