http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108060165-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate | 2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108060165-B |
titleOfInvention | Alpha-subunit-combined F1F0-ATP synthetase RNA inhibitor and application thereof |
abstract | The invention relates to a medicine for resisting F1F0-ATP synthetase activity. The inhibitor is combined with an alpha subunit of F1F0-ATP synthetase to release the alpha subunit from a mitochondrial membrane into cytoplasm, so that F1F0-ATP synthetase is depolymerized, the ATP synthetase activity is reduced, intracellular ATP synthesis is inhibited, and the inhibitor has the characteristics of high inhibition efficiency, convenience in synthesis, low cost and the like. The technical scheme is as follows: coaxial cable fatigue detection equipment, its characterized in that: an F1F0-ATP synthase RNA inhibitor (designated dsRNA-184-U), characterized in that the sequence of the inhibitor is as follows: 5'-UGGAUGGAGAACUGAUAAGGGU-3' are provided. |
priorityDate | 2017-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.