http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108060123-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-727 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-01 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0656 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
filingDate | 2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108060123-B |
titleOfInvention | Target regulation system and kit for somatic cell dedifferentiation and application |
abstract | The invention discloses a target point regulation and control system for somatic cell dedifferentiation, a kit and application. The target point regulation system regulates somatic cells as follows: inhibition of PKC activity, and inhibition of DNMT activity and/or inhibition of HMT activity and/or inhibition of histone demethylase activity; key targets for corresponding regulation include PKC, and DNMT and/or HMT and/or histone demethylases; the somatic cell is a differentiated cell. The target regulation and control system provided by the invention can promote the efficiency of transdifferentiation of small molecule inducer cells into different types of functional target cells, and has the advantages of definite action target, clear components, maturation stability, easiness in quality control and large-scale production. |
priorityDate | 2016-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 202.