http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108060117-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-84 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0604 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-073 |
filingDate | 2017-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-108060117-B |
titleOfInvention | Method for improving pig cloned embryo development efficiency |
abstract | The invention relates to the field of animal cloning methods, in particular to a method for improving the development efficiency of cloned pig embryos. The method mainly comprises the step of adding the uterine fluid of the sow into the basic culture fluid of the porcine cloned embryo. The method of the invention obviously improves the blastocyst rate of early development of cloned embryos and the total cell number in blastocysts. Transcriptome sequencing results from early embryos showed that addition of the sow uterine fluid culture reduced the number of differentially expressed genes between cloned embryos and normal in vivo fertilized embryos. Most importantly, the delivery rate and the litter average number of the recipient sows of the cloned embryos are also improved by adding the uterine fluid of the sows, which shows that the method effectively improves the final efficiency of the in-vivo development of the cloned embryos. |
priorityDate | 2017-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.