http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108059673-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate | 2017-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108059673-B |
| titleOfInvention | Method for separating immunoglobulin IgG from human serum |
| abstract | The invention relates to a method for separating immunoglobulin IgG from human serum, which comprises the following steps: 1) diluting human serum with buffer solution, adjusting pH to 6.0-8.0, and filtering with filter membrane to obtain human serum sample; 2) loading a human serum sample into a chromatographic column filled with a combined bionic chromatography medium, washing with an equilibrium buffer solution, eluting with an elution buffer solution, and collecting the eluate to obtain an immunoglobulin IgG solution; the combined bionic chromatography medium comprises a chromatography matrix and a combined ligand, wherein the chromatography matrix is a hydrophilic porous microsphere with hydroxyl; the sequence of the combined ligand is phenylalanine-tyrosine-glutamine-5-aminobenzimidazole; 3) and (3) carrying out ultrafiltration concentration on the immunoglobulin IgG solution to obtain the immunoglobulin IgG. The method can improve the efficiency and purity of immunoglobulin IgG separated from blood. |
| priorityDate | 2017-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.