http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108051550-B

Outgoing Links

Predicate Object
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-80
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
filingDate 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-108051550-B
titleOfInvention Method for determining main acidic substances in cell culture medium
abstract The invention relates to a method for determining the main acidic substances in a cell culture medium, comprising the following steps: measuring the pH value of the cell culture medium before the culture is started, and recording the pH value as an A value; taking a culture medium from a bioreactor for culturing cells, measuring the pH value of the culture medium, and recording as a B value; shaking the cell culture medium to enable gas in the cell culture medium to overflow, and measuring the pH value of the culture medium after the gas overflows and recording the pH value as a C value; comparing the magnitude between the A value, B value and C value to determine the major species of the acidic substance in the cell culture medium. The method can quickly and accurately determine the type of the main acidic substance in the culture medium, is favorable for removing or neutralizing the acidic product in the culture medium in a subsequent targeted manner, and improves the efficiency and the cost performance.
priorityDate 2017-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106987553-A
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID417109324
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID612
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457698762
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID280

Total number of triples: 17.