| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fb38ebd40c70e97cc5f1519c6699162 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate |
2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45c95b6c7d0fe082033f505d13c5c1bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ff3f1bd67de2d5f906c34bc36713866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ef5488bae05e8469b2c282172c635f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae3801825d60e9cca9eefd20f85de8d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62b61fa5efd7aae2a105ff97e5896d0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a12ca6859f6f6e06b1c1f308b642ede
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef3f00fbc0429dc6d10250e8e425293c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c99c41597b9891075811ac3ac264bad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ed5e374dd9744a4e187cae387048a6 |
| publicationDate |
2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-108047291-A |
| titleOfInvention |
A kind of synthetic method of Houttuyfotin hybrid flavonoids |
| abstract |
The invention discloses a method for synthesizing houttuyfotin hybrid flavonoids. In the present invention, the compound 1-I is reacted with an acetylating reagent; the obtained 1-II and 1-undecyne are stirred and reacted in the dark under the protection of an inert gas; the obtained 1-III is reacted with a base at -10-30°C Reaction under stirring; 1-IV obtained and 2-acetyl-3,5-bis(benzyloxy)phenol reacted; 1-V obtained was reacted with iodine and DMSO at 50-150°C with stirring; The obtained 1-VI is reacted with potassium persulfate compound salt and p-toluenesulfonic acid under the condition of pH value = 9-12; the obtained 1-VII is mixed with acid and water at 80-130°C under reflux and stirring Reaction; stirring and reacting the obtained 1-VIII with bromosugar; deprotecting the obtained 1-IX to obtain 1-X; reacting 1-X with an oxidizing agent to obtain 1-XI. The method is simple and the yield is high. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109810115-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109810115-A |
| priorityDate |
2017-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |