http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108047261-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 |
| filingDate | 2018-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108047261-B |
| titleOfInvention | Preparation method of clitorium |
| abstract | The invention discloses a preparation method of Cliborol and an intermediate for preparing the Cliborol, wherein the method comprises the following steps: (1) reacting, for example, 2-halo-5- (4-cyanophenoxy) benzyl alcohol acetate with bis (pinacolato) diboron in an organic solvent in the presence of a palladium catalyst under basic conditions to produce, for example, 2-acetoxymethyl-4- (4-cyanophenoxy) phenylboronic acid pinacol ester; (2) the krebs-n-ol is prepared, for example, by reacting 2-acetoxymethyl-4- (4-cyanophenoxy) phenylboronic acid pinacol ester in a reaction solvent under acidic or basic conditions. The method has the advantages of mild reaction conditions, easy operation, high reaction yield, simple post-treatment and lower cost, and is suitable for industrial production. |
| priorityDate | 2018-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.