http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108047160-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 |
| filingDate | 2018-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108047160-B |
| titleOfInvention | 2- (2-benzylhydrazono) -5-acylthiazole and medical application thereof |
| abstract | The invention relates to 2- (2-benzylhydrazono) -5-acyl thiazole shown as a formula I, pharmaceutically acceptable salts thereof, a pharmaceutical composition and application thereof in preparing influenza virus neuraminidase inhibitors. Wherein R is selected from: methyl, ethyl, C 3 ～C 4 Straight chain or C 3 ～C 4 A branched alkyl group; r 1 Selected from: hydrogen, C 1 ～C 2 Alkyl radical, C 3 ～C 4 Straight chain or C 3 ～C 4 A branched alkyl, fluoromethyl, difluoromethyl, trifluoromethyl, bromomethyl, dibromomethyl, tribromomethyl, chloromethyl, dichloromethyl, or trichloromethyl group; x 1 、X 5 Selected from: hydrogen, deuterium, C 1 ～C 2 Alkyl, hydroxy, methoxy, ethoxy, fluoro, chloro, bromo, iodo, nitro, amino, methylamino, dimethylaminoAmino, acetylamino, carboxyl, methoxycarbonyl or ethoxycarbonyl; x 2 、X 4 Selected from: hydrogen, deuterium, C 1 ～C 2 Alkyl radical, C 3 ～C 4 Straight or branched chain alkyl, hydroxy, methoxy, ethoxy, fluoro, chloro, bromo, iodo, nitro, amino, methylamino, dimethylamino, acetylamino, carboxy, methoxycarbonyl or ethoxycarbonyl; x 3 Selected from: hydrogen, deuterium, C 1 ～C 2 Alkyl, hydroxy, methoxy, ethoxy, fluoro, chloro, bromo, iodo, nitro, amino, methylamino, dimethylamino, acetylamino, carboxy, methoxycarbonyl or ethoxycarbonyl. |
| priorityDate | 2018-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.