| abstract |
A compound with chemical structural formula I, wherein n is 0 or 1; X is N or C-R 1 ; R 1 is H or Cl; R 2 and R 3 are each independently H, halogen or alkyl; Ar is Substituted or unsubstituted phenylene, or naphthylene, wherein said substituted or unsubstituted phenylene is A or B and said naphthylene is C; R 4 is H, halogen, or Alkyl; R 5 is H, halogen, alkyl, alkoxy, or hydroxy; R 6 is H or hydroxy; and R 7 is unsubstituted or substituted aryl. The compound has SHP-1 agonist activity and can be used for treating cancer. |