http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108026014-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J27-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 |
| filingDate | 2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108026014-B |
| titleOfInvention | Preparation method of optically active 2-(2-fluorobiphenyl-4-yl)propionic acid |
| abstract | The invention provides a novel preparation method of optically active 2-(2-fluorobiphenyl-4-yl)propionic acid. The present production method is characterized by an organometallic reagent prepared by reacting the compound represented by the formula [1] with magnesium or the like in the presence of a catalytic amount of a nickel compound and a catalytic amount of an optically active compound represented by the formula [3] Reaction with the compound represented by the formula [2] to obtain the compound represented by the formula [4], so that the obtained compound represented by the formula [4] is converted into the compound represented by the formula [5] or a pharmaceutically acceptable salt thereof . |
| priorityDate | 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 110.