| abstract |
A 1,3-diphenyl-1-propanol and a preparation method thereof relate to the technical field of chemical synthesis. The preparation method of 1,3-diphenyl-1-propanol provided by the invention comprises the following steps: benzaldehyde and acetophenone are catalytically reacted under the effect of dibenzylamine trifluoroacetate and catalyst to obtain 3-hydroxyl -1,3-diphenyl-1-acetone; the 3-hydroxyl-1,3-diphenyl-1-acetone is obtained through Huang Minglong reduction reaction to obtain 1,3-diphenyl-1-propanol; wherein , the catalyst is L-proline or D-proline. The above-mentioned preparation method is simple to operate and low in cost, and can prepare products with satisfactory optical purity. In addition, the present invention also relates to 1,3-diphenyl-1-propanol obtained by using the above-mentioned preparation method. |