http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107998453-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate | 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107998453-B |
| titleOfInvention | Surface-modified acellular matrix and modification method thereof |
| abstract | The invention belongs to the field of tissue engineering, and particularly relates to a surface modification method of an acellular matrix. The modification method comprises the following steps: (1) performing carboxyl activation on the acellular matrix; (2) carrying out carboxyl protection on phenylalanine or phenylalanine derivatives, and carrying out graft modification on the phenylalanine or phenylalanine derivatives subjected to carboxyl protection and carboxyl of acellular matrixes through amino groups of the phenylalanine or phenylalanine derivatives; (3) and performing post-treatment on the grafted and modified acellular matrix to obtain the surface-modified acellular matrix. The modified acellular matrix has the functions of resisting infiltration of tumor cells and inflammatory cells, resisting infection, resisting degradation of matrix metalloproteinase and lactic acid and improving inflammatory environment, and can be used for postoperative tissue repair of tumor treatment. |
| priorityDate | 2017-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 162.