| abstract |
The invention provides an artificial skin for repairing a skin wound surface, and a preparation method and application thereof. The preparation method of the artificial skin comprises the steps of preparing a natural polymer solution, preparing a modified biodegradable polymer material and a modified biodegradable polymer solution, mixing the natural polymer solution and the modified biodegradable polymer solution to prepare a composite gel, and then carrying out three-dimensional printing on the prepared composite gel to prepare the artificial skin. The artificial skin has a three-dimensional network porous structure, and is beneficial to the adhesion, proliferation, ingrowth and vascularization formation of skin cells. The artificial skin is used after swelling in phosphate buffer solution or physiological saline. |