http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107987042-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107987042-B |
| titleOfInvention | Benzofuran-containing acetylpiperazine compound and application thereof in medicine |
| abstract | An acetylpiperazine compound containing benzofuranyl and application thereof in medicine relate to a compound and application thereof in medicine; the invention relates to an acetylpiperazine compound containing benzofuran, an analogue thereof, pharmaceutically applicable salt thereof or a stereoisomer and a prodrug thereof, which are used as lipase inhibitors, and have the structural general formula shown as the right formula: in the structural formula, Ar can be independently selected from phenyl, C1-C4 alkyl substituted phenyl, C1-C4 alkoxy substituted phenyl, and halogen substituted phenyl. The new compound as lipase inhibitor can inhibit the activity of lipase, prevent the conversion and absorption of fat and directly discharge the fat from excrement, and as a novel nutrition-reducing absorbent, the new compound can act on gastrointestinal tract, prevent the catalytic decomposition of lipase and inhibit the absorption of partial fat ingested by diet, and is suitable for obesity including healthy obesity patients and obesity patients with non-insulin dependent diabetes mellitus. |
| priorityDate | 2017-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.