| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a431cf4c64da0f89eccaa9aa30b43b7f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-3246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-3223
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-3142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-413
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2261-1424 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G61-123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G61-126
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6402 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G61-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate |
2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f55cb9ab928c73409a603c60abf915d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27f8b0923da578c5b08984f0ed6fb222
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb1da1eba2126eeb2d42143157b7b858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7076e1f45e7d067acf235f3b0f396bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03d02ce95f84d5490a53b20664f882ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_111ceac603d7b4b5433a73236c44e454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecd191536c91d553b79e45dd0e3f5bdc |
| publicationDate |
2018-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-107973901-A |
| titleOfInvention |
Preparation and application method of dual bio-optical window targeting nano-bioprobe |
| abstract |
The invention discloses the preparation and application of a double biological optical window (650-1000nm) targeting nano biological probe. First, the dienyl fluorene derivatives and aromatic heterocyclic groups with narrow band gaps are used for two-component alternating copolymerization, and organometallic catalyzed Heck reaction is carried out to obtain neutral polymers, and then a main polymer is obtained by quaternization reaction. The chain is a cationic water-soluble conjugated polymer with a D-π-A structure and two-photon absorption and near-infrared emission properties. Cationic water-soluble conjugated polymers and oppositely charged tumor-targeting biomolecules are prepared by nanoprecipitation method to prepare targeted nanobiological probes, which can realize tumor-targeted two-photon fluorescence cell imaging with dual bio-optical windows. |
| priorityDate |
2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |