http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107964066-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-76
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76
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filingDate 2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107964066-B
titleOfInvention Functionalization responsive to temperature type polymer and preparation method thereof and the application in (PTM) protein detection
abstract The invention discloses functionalization responsive to temperature type polymer and preparation method thereof and the application in (PTM) protein detection.The structural formula of the functionalization responsive to temperature type polymer is as shown in formula I: in formula I, R CH 2 , r value is 0 or 1, and m is the random natural number between 20~750, and n is the random natural number between 110~1120; For horseradish peroxidase unit.Functionalization responsive to temperature type polymer of the invention be obtained by Raolical polymerizable with largely can decorating site linear polymer, the responsive to temperature type polymer for carrying multiple HRP and a large amount of triphenyl phosphorus groups can be obtained after functional modification.Compared with using the antibody strategies for only carrying single HRP in conventional method, the increase of HRP and triphenyl phosphorus radical amount can effectively improve its binding ability with nitrine label target protein and chemiluminescent signal amplification effect.
priorityDate 2017-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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