Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cc4e13141d402ceb885f368dfa042348 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2387-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2329-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L29-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L87-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 |
filingDate |
2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1bd48600d4970cfcc55f30d5a3ea27b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b4369a4c90205994b1ac806d022d62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d47de818c007de184819310f5dffbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7b607cfe2d863ff1e7619bdf6b8ae4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94503510ec202a3e0eb6101f43d6179c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_579eaa3b6cdb6ea1ddfa6d4474e1dcaf |
publicationDate |
2018-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-107955186-A |
titleOfInvention |
A kind of low molecular weight polyethylene alcohol selfreparing hydrogel and preparation method thereof |
abstract |
The invention belongs to polymeric biomaterial technical field, discloses a kind of low molecular weight polyethylene alcohol selfreparing hydrogel and preparation method thereof.Low molecular weight polyethylene alcohol is reacted under the conditions of succinic anhydride and p-methyl benzenesulfonic acid, obtains carboxyl acid modified PVA;Then carboxyl acid modified PVA and amino modified cholic acid and single (6 ethylenediamines 6 deoxygenate) beta cyclodextrin are reacted respectively, obtains PVA CA and PVA CD;Finally PVA CA and PVA CD are dissolved in the hot water respectively, then by both solution mixing self assemblies, obtain the low molecular weight polyethylene alcohol selfreparing hydrogel.Gained gel of the invention has excellent biocompatibility, good mechanical performance and self-healing properties.And the mechanical performance of selfreparing hydrogel can be adjusted by adjusting cholic acid graft ratio, wider biomedical applications can be adapted to. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124729-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109320673-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124729-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114380973-A |
priorityDate |
2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |