http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107955029-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-12 |
| filingDate | 2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107955029-B |
| titleOfInvention | Preparation method of Raschindde |
| abstract | The invention discloses a LeixinaA preparation method of German medicine, belonging to the technical field of chemical medicine synthesis process. The invention takes the compounds of formula Les-01 and Les-02 as raw materials to prepare formula Les-03, then adds Les-04 to prepare Les-05, the Les-05 has high selectivity during coupling, so that the purity of the reaction product is high, the post-treatment is easy, and the quality of the obtained final product is controllable; les-07 is prepared by performing Suzuki coupling reaction on Les-05 and Les-06, the Suzuki coupling reaction has high reliability and good repeatability, and finally, the protecting group is removed to obtain Ravinard. The method has the advantages of short process route, high yield and low cost, all the used reagents are nontoxic or low-toxicity conventional reagents, the method is basically harmless to operators and environment, the whole process is simple and convenient to operate, the process stability is good, the quality of the obtained final product is controllable and stable, and the method is suitable for commercial production. |
| priorityDate | 2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.