http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107937514-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107937514-B |
titleOfInvention | Application of primer in preparation of product for diagnosing pulmonary tuberculosis |
abstract | The invention provides an application of a primer in the preparation of a product for diagnosing pulmonary tuberculosis, which utilizes a circular RNA expression profile chip technology to screen a circRNA (circZFY) which is obviously and highly expressed in the plasma of a pulmonary tuberculosis patient through differential analysis, wherein the transcription region of the circZFY is positioned on a chromosome 12 and has a full length of 1909 bp. Compared with the plasma of a healthy control person, the circZFY is remarkably and highly expressed in the plasma of the tuberculosis patient, and the plasma circZFY expression level of the tuberculosis patient is further proved to be remarkably higher than that of the healthy control person in a large-sample fluorescent quantitative PCR experiment. The plasma circZFY expression level of tuberculosis patients was significantly reduced after 6 months after anti-tubercular treatment. The primers for screening the circZFY are prepared, and the circZFY provides a new idea for researching the pathogenesis of the pulmonary tuberculosis and also provides a new target for early diagnosis and prognosis monitoring of the pulmonary tuberculosis. |
priorityDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 189.