http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107935848-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-612 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-612 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 |
| filingDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107935848-B |
| titleOfInvention | Hexaalizarin derivative and preparation method and application thereof |
| abstract | The invention discloses a hexaalizarin derivative. The hexaalizarin derivative has the following chemical structural formula: in an alkaline environment provided by triethylamine, dicyclohexylcarbodiimide is used as a dehydrating agent, 4-dimethylaminopyridine is used as a catalyst, and hexaalizarin and ibuprofen undergo an esterification reaction to obtain the hexaalizarin derivative. Acute toxicity test results show that the hexaalizarin derivative is nontoxic, pharmacodynamic tests show that the hexaalizarin derivative has better anti-inflammatory and analgesic effects than hexaalizarin and ibuprofen original drugs which are physically mixed in an equivalent amount, and the hexaalizarin derivative has potential application in preparing anti-inflammatory and analgesic drugs. |
| priorityDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.