| abstract |
The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to antagonist antibodies or fragments thereof that bind to human OX40, comprising the heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO:1, and/or the heavy chain comprising the amino acid sequence of SEQ ID NO:2 CDR2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO:3; and/or a light chain CDR1 comprising the amino acid sequence of SEQ ID NO:4, and/or a CDR1 comprising the amino acid sequence of SEQ ID NO:5 A light chain CDR2, and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO:6. |