| abstract |
The present invention relates to the preparation method of structural formula three classes lactone as follows： This method step：Oxalyl chloride is added drop-wise in the dichloromethane solution of dimethyl sulfoxide at 78 10 DEG C, then adds unsaturated olefin(e) acid, in 78 30 DEG C of reactions, obtains the lactone of alkylthio group substitution, yield 90% or so. |