| abstract |
The coaxial regeneration vessel bracket of medicine and its combination process preparation method are manually carried the invention discloses a kind of, the intravascular stent has three-decker, the preparation of different process method is respectively adopted, wherein inner layer material selects Deferoxamine DFO+PVA sandwich layer solution and PCL shell solution, using coaxial electrically spun forming technology；Intermediate layer material selects PVA+SA mixed solution, is crosslinked using infusion process forming technology, and after electrospinning outer layer using calcium chloride；Cladding material selects gentamicin GS+PVA sandwich layer solution and PCL shell solution, using coaxial electrically spun forming technology.The present invention prepares three layers of load medicine intravascular stent using two kinds of process combining different materials, and simulates the three-decker of native blood vessels very well, and time and success rate needed for shortening in vitro culture transplanting have broad prospects in clinical application. |