abstract |
The invention relates to a [1,2,4]triazolo[1,5-a]pyridine compound, a preparation method and a medical application thereof. In particular, the present invention relates to a compound represented by general formula I, a preparation method thereof, a pharmaceutical composition containing the compound, and its use as a JAK kinase inhibitor. The compound and the pharmaceutical composition containing the compound can be used for Treatment of diseases associated with JAK kinase activity, such as inflammation, autoimmune disorders, cancer, etc. Wherein the definition of each substituent in the general formula I is the same as the definition in the description. |