| abstract |
The invention discloses a kind of method of metal material surface covalence graft biomolecule.First in metal implant material surface construction DLC film, then film is activated, and then immersed the material in containing in the biomolecule solution for promoting osteogenesis function, you can by biomolecule covalence graft on metal implant material surface.On the other hand, the technology of the present invention is easy to operate, and technique is simple, and reaction condition is gentle, it can carry out at normal temperatures, efficiency high, cost is low, favorable repeatability, follow-up cleaning procedure is simple, and without using silane coupler and crosslinking agent, remains risk in the absence of reagent, be advantageous to industrialized production.Therefore, product prepared according to the methods of the invention has very high application prospect in medical embedded material field. |