http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107875392-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2017-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107875392-B |
| titleOfInvention | Composite nano graphene oxide drug carrier and preparation method thereof |
| abstract | A composite nano graphene oxide drug carrier is a drug carrier which combines a natural antitumor extract wedelolactone and a photosensitizer indocyanine green to the surface of nano graphene oxide together through pi-pi accumulation. The preparation method of the composite nano graphene oxide drug carrier mainly comprises the following steps: firstly, treating graphene oxide by using an ultrasonic means to obtain nano graphene oxide, and then loading wedelolactone and indocyanine green on the surface of the nano graphene oxide in sequence by using a pi-pi stacking effect. The preparation method is simple, the particle size of the graphene oxide is controlled to be 100-200 nm, the circulation time of the drug carrier in vivo is prolonged, the composite nano graphene oxide drug carrier can absorb near infrared light of 600-900 nm and convert light energy into heat energy to realize photo-thermal treatment, and active oxygen is generated under the irradiation of near infrared light of 808nm to realize the purpose of photodynamic treatment. |
| priorityDate | 2017-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.