http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107868107-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65613 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 |
filingDate | 2017-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107868107-B |
titleOfInvention | Refining method of high-purity ceftaroline fosamil |
abstract | The invention relates to a refining method of high-purity ceftaroline fosamil, belonging to the technical field of medicines. The specific technical scheme of the invention is as follows: adding the crude product of ceftaroline fosamil benzimidazole into the mixed solvent at the temperature of 30 ℃, and stirring for dissolving; stirring and dripping methanol; starting to cool, keeping the same rotating speed, stopping cooling at-5 ℃, and continuously stirring; filtering, soaking the filter cake in methanol at-5 deg.C, suction filtering, washing, spreading the filter cake in a tray with a thickness of 1cm, and drying under reduced pressure at 15 deg.C to obtain refined ceftaroline fosamil. The method has the advantages of simple and easy operation, high yield and suitability for industrial mass production. |
priorityDate | 2017-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.