http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107865983-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-45 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate | 2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107865983-B |
titleOfInvention | Medicine stent and preparation method thereof |
abstract | The invention belongs to the field of medical appliances, and particularly relates to a drug stent and a preparation method thereof. The drug stent comprises a stent body and a drug composition distributed on the stent body, wherein the drug composition consists of amlexanox, paclitaxel, sirolimus and aspirin. The preparation method comprises the following steps: first, a mixed powder or solution of the pharmaceutical composition is prepared, and then the prepared mixed powder or solution is used to load the drug on the surface of the stent body through a dripping, burying or coating method. The invention discovers that the composition of amlexanox, paclitaxel, sirolimus and aspirin has high activity of inhibiting smooth muscle cell proliferation, and after the composition is applied to a drug stent, compared with the current commonly used drug eluting stent, the composition also has the characteristic of low endothelial cell growth inhibition, so that the composition can prevent the incidence rate of vascular restenosis in the PTCA postoperative treatment process, and can not delay endothelial repair. |
priorityDate | 2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.