http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107854452-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_879f77877b2631056b3f2c9fbb15cb9b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_960f8d7b116e5eb2f58c45758024c9ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfd68cb051cbbf9c012c74932223220c |
| publicationDate | 2018-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107854452-A |
| titleOfInvention | A kind of bromhexine hydrochloride sustained release capsule and preparation method thereof |
| abstract | The invention discloses a bromhexine hydrochloride slow-release capsule and a preparation method thereof, comprising 40-60 parts of bromhexine hydrochloride, 30-60 parts of filler, 2-8 parts of lactose, 1-5 parts of pregelatinized starch, lubricating 0.5-1 part of sweetener and 1-3 parts of sweetener are stirred, mixed, and poured into a fluidized bed to make capsules. The results of comparing the prepared bromhexine hydrochloride sustained-release capsules with those of the commercially available antitussive tablets show that the present invention has fast disintegration, high dissolution rate and dissolution rate, short time to peak blood drug concentration, rapid release-absorption, complete tablet appearance, It has strong hardness, delicate and comfortable taste, and no gritty feeling; compared with the existing technology of preparing orally disintegrating tablets by freeze-drying, vacuum drying, and spray-drying methods, the present invention does not require special production equipment and conditions, nor does it require special packaging , the preparation process is simple, the cost is low and the benefit is high. |
| priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.