abstract |
The present invention relates to PYY compounds having amino acid modifications 7Lys, 30Trp and 31Leu, and in addition 22Ile and/or 28Tyr, and derivatives thereof. The compounds of the present invention are selective Y2 receptor agonists. The present invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as pharmaceutical uses of the PYY compounds. |