http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107840867-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J63-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0652 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-80 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate | 2017-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107840867-B |
| titleOfInvention | A kind of 23- aldehyde asiatic acid, preparation method and the application in stem cell field |
| abstract | The invention discloses a kind of 23- aldehyde asiatic acid, preparation method and in the application of stem cell field.The present invention provides a kind of new asiatic acid derivative -23- aldehyde asiatic acids, and provide the preparation method of the 23- aldehyde asiatic acid, and step includes: step S1, bioconversion: take in plum forests mould spore suspension access sterile liquid culture solution and cultivate 2d；It takes appropriate asiatic acid to be added in sterile liquid culture solution under aseptic condition, continues to cultivate 3d；Step S2, isolates and purifies: culture solution filters to take filtrate, is splined on macroreticular resin, it is eluted with 40%, 75% ethanol water, 75% ethanol eluate is collected, is separated after concentration with reverse phase preparative liquid chromatography, the corresponding elution fraction of 23- aldehyde asiatic acid is collected according to chromatogram.Applicants have found that 23- aldehyde asiatic acid can be with inducing bone mesenchymal stem cell Osteoblast Differentiation. |
| priorityDate | 2017-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.