http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107837418-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3847 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C25D9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3834 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C25D9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-06 |
| filingDate | 2017-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107837418-B |
| titleOfInvention | Preparation method and application of biotinylation titanium plate loaded with adipose-derived stem cell microvesicles |
| abstract | The invention provides a preparation method of a biotinylation titanium plate loaded with adipose-derived stem cell microbubbles, which mainly comprises the following steps: (1) the preparation method comprises the following steps of (1) titanium sheet pretreatment, (2) preparation of biotinylated polypyrrole (Biotin-Ppy) titanium sheet, (3) preparation of biotinylated adipose-derived stem cell microvesicle (ASCs-MV), (4) composite inoculation of Biotin-labeled ASCs-MV and biotinylated polypyrrole titanium sheet, and preparation of the biotinylated titanium sheet loaded with adipose-derived stem cell microvesicle. The ASCs-MV has good angiogenesis promoting and stem cell proliferation promoting properties, and by utilizing an avidin-biotin system with a cascade amplification effect, the ASCs-MV can successfully carry out surface modification on a biotinylated polypyrrole titanium sheet, so that the osteogenic and angiogenetic capabilities of osteoblasts are effectively improved, and a potential material modification method is provided for bone regeneration. |
| priorityDate | 2017-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 140.