http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107837239-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_879f77877b2631056b3f2c9fbb15cb9b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-10 |
| filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_960f8d7b116e5eb2f58c45758024c9ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfd68cb051cbbf9c012c74932223220c |
| publicationDate | 2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107837239-A |
| titleOfInvention | A kind of bromhexine hydrochloride nano-dispersion tablet and preparation method thereof |
| abstract | The invention discloses a bromhexine hydrochloride nano-dispersion tablet and a preparation method thereof, comprising 40-60 parts of bromhexine hydrochloride, 30-60 parts of a filler, 2-8 parts of swelling auxiliary materials, 1-5 parts of an adhesive, 0.5-1 part of lubricant and 1-3 parts of sweetener are prepared by stirring, mixing, granulating and tableting with a plunger extruder. The results of comparing the prepared bromhexine hydrochloride dispersible tablets with those of the commercially available antitussive tablets show that the present invention has fast disintegration, high dissolution rate and dissolution rate, short time to peak blood drug concentration, rapid release-absorption, complete tablet appearance, and Stronger hardness, delicate and refreshing taste, no gritty feeling; compared with the existing techniques for preparing orally disintegrating tablets by freeze-drying, vacuum-drying, and spray-drying methods, the present invention does not require special production equipment and conditions, nor does it require special packaging. The preparation process is simple, the cost is low and the benefit is high. |
| priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.