http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107827882-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
filingDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107827882-B |
titleOfInvention | A kind of razaxaban analog and its purposes for treating thrombus |
abstract | The invention belongs to field of medicinal chemistry, and in particular to a kind of razaxaban analog and its purposes for treating thrombus.Razaxaban analog of the present invention is that aspirin and chloride reagent act on after generating 2- acetoxyl group chlorobenzoyl chloride and be condensed generation under certain condition with 4- [4- [(5S) -5- (aminomethyl) -2- carbonyl -3- oxazolidinyl] phenyl] -3- morpholine ketone again.The invention also discloses the pharmaceutical salts of razaxaban analog, the pharmaceutical composition comprising compound or its salt, and the purposes of the inhibitor as the FXa factor, further prepare the medical usage in anticoagulant.More particularly to it as the purposes in preparation prevention or treatment thrombosis or thrombosis drug. |
priorityDate | 2017-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.