http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107827864-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48 |
| filingDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107827864-B |
| titleOfInvention | Method for separating chemical components of methylene chloride extraction part of piper longum composition and application |
| abstract | The invention belongs to the technical field of medicine preparation, relates to a method for extracting and separating chemical components of medicinal plants, and particularly relates to a method for separating chemical components of a methylene chloride extraction part of a piper longum composition and application thereof. The invention extracts and removes oil from the pepper and long pepper composition by a carbon dioxide supercritical fluid method, extracts dregs of a decoction by 70 percent ethanol, concentrates the dregs of the decoction, extracts the dregs of the decoction by dichloromethane, recovers the dichloromethane, and dries the dichloromethane extraction part; performing systematic separation on the chemical components of the dichloromethane extraction part by normal phase silica gel column chromatography, high pressure preparative liquid chromatography, reversed phase ODS column chromatography, LH-20 gel column chromatography and preparative thin layer chromatography to obtain 10 compounds. Pharmacodynamic test results show that 10 compounds separated from dichloromethane extraction parts of the piper longum composition have protective activity on nerve cells, wherein the content of the compound 10: dibutyl phthalate activity is best. Has important significance for the research and development and the quality control of the cerebral apoplexy treatment drug. |
| priorityDate | 2017-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.