http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107827821-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01C1-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01C1-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01D5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-26 |
| filingDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107827821-B |
| titleOfInvention | Continuous flow clean production process of pyrazolone series products |
| abstract | The invention discloses a continuous flow clean production process of pyrazolone series products, which comprises the steps of reacting aromatic amine with a sulfuric acid aqueous solution for 0.5-2h to obtain an aromatic amine sulfate solution; the aromatic amine sulfate solution and the sodium nitrite solution enter a premixer at the same time, and enter a continuous flow reactor for diazotization after being mixed; continuously adding the generated diazonium salt into an aqueous solution of ammonium sulfite and ammonium bisulfite to carry out reduction reaction; adding sulfuric acid solution after the reduction reaction is finished, and carrying out hydrolysis reaction at 70-120 ℃; neutralizing after hydrolysis reaction, controlling the pH value to be 2-5, carrying out condensation reaction with diethylamine at 40-70 ℃, cooling to 10-40 ℃ after reacting for 1-3 hours, filtering and drying to obtain a pyrazolone product; after the mother liquor is extracted by solvent or decolored by active carbon, the mother liquor is evaporated and concentrated, and is cooled in a sectional gradient way, and is crystallized and separated to obtain ammonium sulfate and sodium sulfate. The invention has less side reaction and high diazotization yield, and can generate a series of products. |
| priorityDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.